منابع مشابه
Intestinal microflora and metabolic diseases.
Recent advances in molecular sequencing technology have allowed researchers to answer major questions regarding the relationship between a vast genomic diversity-such as found in the intestinal microflora-and host physiology. Over the past few years, it has been established that, in obesity, type 1 diabetes and Crohn's disease-to cite but a few-the intestinal microflora play a pathophysiologica...
متن کاملAutochthonous Intestinal Microflora
Based on agglutination, complement fixation, bactericidal, and opsonization tests, it is evident that suspensions of a Bacteroides sp. isolated from the mouse intestine and given by parenteral routes do not initiate antibody formation in mice. Rats also respond poorly to the antigenic stimulus. In contrast, suspensions of other bacterial species isolated from the rodent intestine are highly imm...
متن کاملIntestinal absorption of peptides by coupling to bile acids.
Poor intestinal absorption of peptides greatly limits their use as drugs for the treatment of chronic diseases. Since bile acids are efficiently absorbed by an active, Na(+)-dependent transport system in the ileum of mammals, model peptides of different chain length were attached to the 3-position of modified 3 beta-(omega-amino-alkoxy)-7 alpha, 12 alpha-dihydroxy-5 beta-cholan-24-oic acid. The...
متن کاملeffect of organic acids on intestinal microflora and morphology of broiler chickens
the effect of dose and regimen of organic acids on micro-flora and morphology of small intestine were studied in a total of 300 male day old broiler chicks using completely randomized design. salkil had no significant effects on the number of villi per view field and percent of convoluted villi. salkil had a significant effect on the number of tongue, ridge shaped (p
متن کاملIsolation of a bile salt sulfatase-producing Clostridium strain from rat intestinal microflora.
Bile acid sulfates, formed in human and rat livers, are desulfated by the intestinal microflora. In our study we first isolated from conventional rat feces an unnamed bacterium, termed strain S1, which desulfated the 5 beta-bile salt 3 alpha-sulfates in vitro and in vivo after association with gnotobiotic rats. Strain S1 also possessed 12 alpha-hydroxysteroid dehydrogenase and bile salt-deconju...
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ژورنال
عنوان ژورنال: Microbiology and Immunology
سال: 1980
ISSN: 0385-5600
DOI: 10.1111/j.1348-0421.1980.tb00578.x